SHORT TELOMERES ASSOCIATE WITH HYPERPHOSPHORYLATED TAU BURDEN IN PRIMARY AGE-RELATED TAUOPATHY

Aging is a major risk factor for hyperphosphorylated tau burden (p-tau). Telomeres lengths (TL) shorten with age and various sources of DNA damage, thus provide a measure of biological age. Additionally, DNA methylation (DNAm) changes over time and may contribute to changes in TL. We hypothesize tha...

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Detalles Bibliográficos
Autores principales: McMillan, Corey, Adhikari, Bandita, Farrell, Kurt, Wolk, David, Lee, Edward, Crary, John, Johnson, F Bradley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765938/
http://dx.doi.org/10.1093/geroni/igac059.1739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765938/
http://dx.doi.org/10.1093/geroni/igac059.1739

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