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THE FOXO3 LONGEVITY GENOTYPE PROTECTS AGAINST MECHANISMS OF CELLULAR AGING IN OKINAWANS

The genetic association of FOXO3 genotypes with human longevity is well established, although the mechanism is not fully understood. We now report on the relationship of the FOXO3 longevity variant rs2802292 with telomere length, telomerase activity, FOXO3 expression and inflammatory cytokine levels...

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Detalles Bibliográficos
Autores principales: Torioge, Trevor, Willcox, D Craig, Shimabukuro, Michio, Donlon, Timothy, Chen, Randi, Allsopp, Richard, Willcox, Bradley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9766350/
http://dx.doi.org/10.1093/geroni/igac059.1736