Genetic engineering of pigs for xenotransplantation to overcome immune rejection and physiological incompatibilities: The first clinical steps

Xenotransplantation has the potential to solve the shortfall of human organ donors. Genetically modified pigs have been considered as potential animal donors for human xenotransplantation and have been widely used in preclinical research. The genetic modifications aim to prevent the major species-sp...

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Detalles Bibliográficos
Autores principales: Lei, Tiantian, Chen, Lin, Wang, Kejing, Du, Suya, Gonelle-Gispert, Carmen, Wang, Yi, Buhler, Leo H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9766364/
https://www.ncbi.nlm.nih.gov/pubmed/36561750
http://dx.doi.org/10.3389/fimmu.2022.1031185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9766364/
https://www.ncbi.nlm.nih.gov/pubmed/36561750
http://dx.doi.org/10.3389/fimmu.2022.1031185

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