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Genetic engineering of pigs for xenotransplantation to overcome immune rejection and physiological incompatibilities: The first clinical steps
Xenotransplantation has the potential to solve the shortfall of human organ donors. Genetically modified pigs have been considered as potential animal donors for human xenotransplantation and have been widely used in preclinical research. The genetic modifications aim to prevent the major species-sp...
Autores principales: | Lei, Tiantian, Chen, Lin, Wang, Kejing, Du, Suya, Gonelle-Gispert, Carmen, Wang, Yi, Buhler, Leo H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9766364/ https://www.ncbi.nlm.nih.gov/pubmed/36561750 http://dx.doi.org/10.3389/fimmu.2022.1031185 |
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