PHOSPHORYLATION OF ULK1 AT S555 IS REQUIRED FOR METABOLIC ADAPTATIONS TO CALORIC RESTRICTION

Unc-51 Like Autophagy Activating Kinase 1 (Ulk1) is responsible for initiating selective degradation of damaged/dysfunctional mitochondria (mitophagy) once phosphorylated at S555 in response to energetic stress. Mitophagy is integral for mitochondrial health and Ulk1 has been implicated to be import...

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Detalles Bibliográficos
Autores principales: Drake, Joshua, Nichenko, Anna, Wiloughby, Orion, Brisendine, Matt, Hays, Garrett, DiGirolamo, Grace, Weingrad, Zach, McMillan, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9766411/
http://dx.doi.org/10.1093/geroni/igac059.1668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9766411/
http://dx.doi.org/10.1093/geroni/igac059.1668

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