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CLINICAL TRIAL OF METFORMIN FOR FRAILTY PREVENTION IN COMMUNITY-DWELLING OLDER ADULTS WITH PRE-DIABETES

BACKGROUND: Metformin may reduce frailty through improving insulin resistance and inflammation, aging mechanisms known to increase frailty risk. We describe a randomized clinical trial of metformin for frailty prevention in community-dwelling older adults with pre-diabetes and provide baseline chara...

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Detalles Bibliográficos
Autores principales: Espinoza, Sara, Wang, Chen-pin, Michalek, Joel, MacCarthy, Daniel, Cortes, Tiffany, Powers, Becky, Musi, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9766609/
http://dx.doi.org/10.1093/geroni/igac059.2117