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LATE-LIFE MORTALITY GWAS IN FLIES IDENTIFIES DIABETES AND OBESITY REGULATED TO REGULATE MORTALITY AND RESILIENCE

Variations in rate of aging in geneticaly heterogenious populations supports the hypothesis that aging is at least partially genetically regulated. However, genetically identical individuals also vary in their time of death. We have observed in D. melanogaster that this variation is genotype-depende...

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Detalles Bibliográficos
Autores principales: Hilsabeck, Tyler, Bar, Sudipta, Wilson, Kenneth, Beck, Jennifer, Nelson, Christopher, Brem, Rachel, Kapahi, Pankaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9766833/
http://dx.doi.org/10.1093/geroni/igac059.1737