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Inhibition of mitosomal alternative oxidase causes lifecycle arrest of early-stage Trachipleistophora hominis meronts during intracellular infection of mammalian cells

Mitosomes are highly reduced forms of mitochondria which have lost two of the ‘defining’ features of the canonical organelle, the mitochondrial genome, and the capacity to generate energy in the form of ATP. Mitosomes are found in anaerobic protists and obligate parasites and, in most of the studied...

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Detalles Bibliográficos
Autores principales: Sendra, Kacper M., Watson, Andrew K., Kozhevnikova, Ekaterina, Moore, Anthony L., Embley, T. Martin, Hirt, Robert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9767352/
https://www.ncbi.nlm.nih.gov/pubmed/36538568
http://dx.doi.org/10.1371/journal.ppat.1011024