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Kalpra: A kernel approach for longitudinal pathway regression analysis integrating network information with an application to the longitudinal PsyCourse Study

A popular approach to reduce the high dimensionality resulting from genome-wide association studies is to analyze a whole pathway in a single test for association with a phenotype. Kernel machine regression (KMR) is a highly flexible pathway analysis approach. Initially, KMR was developed to analyze...

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Detalles Bibliográficos
Autores principales: Wendel, Bernadette, Heidenreich, Markus, Budde, Monika, Heilbronner, Maria, Oraki Kohshour, Mojtaba, Papiol, Sergi, Falkai, Peter, Schulze, Thomas G., Heilbronner, Urs, Bickeböller, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9767414/
https://www.ncbi.nlm.nih.gov/pubmed/36561312
http://dx.doi.org/10.3389/fgene.2022.1015885