Innate immune signaling drives late cardiac toxicity following DNA-damaging cancer therapies

Late cardiac toxicity is a potentially lethal complication of cancer therapy, yet the pathogenic mechanism remains largely unknown, and few treatment options exist. Here we report DNA-damaging agents such as radiation and anthracycline chemotherapies inducing delayed cardiac inflammation following t...

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Detalles Bibliográficos
Autores principales: Shamseddine, Achraf, Patel, Suchit H., Chavez, Valery, Moore, Zachary R., Adnan, Mutayyaba, Di Bona, Melody, Li, Jun, Dang, Chau T., Ramanathan, Lakshmi V., Oeffinger, Kevin C., Liu, Jennifer E., Steingart, Richard M., Piersigilli, Alessandra, Socci, Nicholas D., Chan, Angel T., Yu, Anthony F., Bakhoum, Samuel F., Schmitt, Adam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9767651/
https://www.ncbi.nlm.nih.gov/pubmed/36534085
http://dx.doi.org/10.1084/jem.20220809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9767651/
https://www.ncbi.nlm.nih.gov/pubmed/36534085
http://dx.doi.org/10.1084/jem.20220809

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