Regulation of Αlpha-Synuclein Gene (SNCA) by Epigenetic Modifier TET1 in Parkinson Disease

PURPOSE: Deregulation of SNCA encoding α-synuclein (α-SYN) has been associated with both the familial and sporadic forms of Parkinson disease (PD). Epigenetic regulation plays a crucial role in PD. The intron1 of SNCA harbors a large unmethylated CpG island. Ten-eleven translocation methylcytosine d...

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Detalles Bibliográficos
Autores principales: Guhathakurta, Subhrangshu, Song, Min Kyung, Basu, Sambuddha, Je, Goun, Cristovao, Ana Clara, Kim, Yoon-Seong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Continence Society 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9767688/
https://www.ncbi.nlm.nih.gov/pubmed/36503211
http://dx.doi.org/10.5213/inj.2222206.103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9767688/
https://www.ncbi.nlm.nih.gov/pubmed/36503211
http://dx.doi.org/10.5213/inj.2222206.103

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