Astrocyte-derived exosomal nicotinamide phosphoribosyltransferase (Nampt) ameliorates ischemic stroke injury by targeting AMPK/mTOR signaling to induce autophagy

Acute ischemic stroke (AIS) is a global cerebrovascular disease with high disability and mortality, which has no effective therapy. Studies have demonstrated that astrocyte-derived exosomes (ADEXs) provided neuroprotection in experimental stroke models. Nevertheless, the role of exosomes derived fro...

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Detalles Bibliográficos
Autores principales: Deng, Yang, Duan, Rui, Ding, Wangli, Gu, Qiuchen, Liu, Manman, Zhou, Junshan, Sun, Jianguo, Zhu, Junrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9767935/
https://www.ncbi.nlm.nih.gov/pubmed/36539418
http://dx.doi.org/10.1038/s41419-022-05454-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9767935/
https://www.ncbi.nlm.nih.gov/pubmed/36539418
http://dx.doi.org/10.1038/s41419-022-05454-9

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