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Adipose-targeted triiodothyronine therapy counteracts obesity-related metabolic complications and atherosclerosis with negligible side effects

Thyroid hormone (TH) is a thermogenic activator with anti-obesity potential. However, systemic TH administration has no obvious clinical benefits on weight reduction. Herein we selectively delivered triiodothyronine (T3) to adipose tissues by encapsulating T3 in liposomes modified with an adipose ho...

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Detalles Bibliográficos
Autores principales: Chen, Kang, Cheong, Lai Yee, Gao, Yuan, Zhang, Yaming, Feng, Tianshi, Wang, Qin, Jin, Leigang, Honoré, Eric, Lam, Karen S. L., Wang, Weiping, Hui, Xiaoyan, Xu, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9767940/
https://www.ncbi.nlm.nih.gov/pubmed/36539421
http://dx.doi.org/10.1038/s41467-022-35470-4