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Adipose-targeted triiodothyronine therapy counteracts obesity-related metabolic complications and atherosclerosis with negligible side effects
Thyroid hormone (TH) is a thermogenic activator with anti-obesity potential. However, systemic TH administration has no obvious clinical benefits on weight reduction. Herein we selectively delivered triiodothyronine (T3) to adipose tissues by encapsulating T3 in liposomes modified with an adipose ho...
Autores principales: | Chen, Kang, Cheong, Lai Yee, Gao, Yuan, Zhang, Yaming, Feng, Tianshi, Wang, Qin, Jin, Leigang, Honoré, Eric, Lam, Karen S. L., Wang, Weiping, Hui, Xiaoyan, Xu, Aimin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9767940/ https://www.ncbi.nlm.nih.gov/pubmed/36539421 http://dx.doi.org/10.1038/s41467-022-35470-4 |
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