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Lymphoid tissue residency: A key to understand Tcf-1(+)PD-1(+) T cells
During chronic antigen exposure, a subset of exhausted CD8(+) T cells differentiate into stem cell-like or progenitor-like T cells expressing both transcription factor Tcf-1 (T cell factor-1) and co-inhibitory receptor PD-1. These Tcf-1(+) stem-like or progenitor exhausted T cells represent the key...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9767944/ https://www.ncbi.nlm.nih.gov/pubmed/36569850 http://dx.doi.org/10.3389/fimmu.2022.1074698 |