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Lymphoid tissue residency: A key to understand Tcf-1(+)PD-1(+) T cells

During chronic antigen exposure, a subset of exhausted CD8(+) T cells differentiate into stem cell-like or progenitor-like T cells expressing both transcription factor Tcf-1 (T cell factor-1) and co-inhibitory receptor PD-1. These Tcf-1(+) stem-like or progenitor exhausted T cells represent the key...

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Detalles Bibliográficos
Autores principales: Ma, Chaoyu, Zhang, Nu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9767944/
https://www.ncbi.nlm.nih.gov/pubmed/36569850
http://dx.doi.org/10.3389/fimmu.2022.1074698