Targeting the PI3K/AKT/mTOR and RAF/MEK/ERK pathways for cancer therapy

The PI3K/AKT/mTOR and RAF/MEK/ERK pathways are commonly activated by mutations and chromosomal translocation in vital targets. The PI3K/AKT/mTOR signaling pathway is dysregulated in nearly all kinds of neoplasms, with the component in this pathway alternations. RAF/MEK/ERK signaling cascades are use...

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Detalles Bibliográficos
Autores principales: Li, Qingfang, Li, Zhihui, Luo, Ting, Shi, Huashan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768098/
https://www.ncbi.nlm.nih.gov/pubmed/36539659
http://dx.doi.org/10.1186/s43556-022-00110-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768098/
https://www.ncbi.nlm.nih.gov/pubmed/36539659
http://dx.doi.org/10.1186/s43556-022-00110-2

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