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IL-4 induces reparative phenotype of RPE cells and protects against retinal neurodegeneration via Nrf2 activation

Retinal degeneration is a kind of neurodegeneration characterized by progressive neuronal death and dysfunction of retinal pigment epithelium (RPE) cells, leading to permanent visual impairment. It still lacks effective therapeutic options and new drugs are highly warranted. In this study, we found...

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Detalles Bibliográficos
Autores principales: Zhou, Tian, Yang, Ziqi, Ni, Biyan, Zhou, Hong, Xu, Huiyi, Lin, Xiaojing, Li, Yingmin, Liu, Chunqiao, Ju, Rong, Ge, Jian, He, Chang, Liu, Xialin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768119/
https://www.ncbi.nlm.nih.gov/pubmed/36539414
http://dx.doi.org/10.1038/s41419-022-05433-0