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IL-4 induces reparative phenotype of RPE cells and protects against retinal neurodegeneration via Nrf2 activation
Retinal degeneration is a kind of neurodegeneration characterized by progressive neuronal death and dysfunction of retinal pigment epithelium (RPE) cells, leading to permanent visual impairment. It still lacks effective therapeutic options and new drugs are highly warranted. In this study, we found...
Autores principales: | Zhou, Tian, Yang, Ziqi, Ni, Biyan, Zhou, Hong, Xu, Huiyi, Lin, Xiaojing, Li, Yingmin, Liu, Chunqiao, Ju, Rong, Ge, Jian, He, Chang, Liu, Xialin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768119/ https://www.ncbi.nlm.nih.gov/pubmed/36539414 http://dx.doi.org/10.1038/s41419-022-05433-0 |
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