Over-expression of miR-183-5p or miR-492 triggers invasion and proliferation and loss of polarity in non-neoplastic breast epithelium

microRNAs (miRNAs) serve as novel noninvasive cancer biomarkers. In an HMT-3522 S1 (S1) breast epithelial risk-progression three-dimensional (3D) culture model, non-neoplastic S1 cells form a fully polarized epithelium. When silenced for the gap junction and tumor suppressor Cx43, Cx43-KO-S1 cells r...

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Detalles Bibliográficos
Autores principales: Naser Al Deen, Nataly, Atallah Lanman, Nadia, Chittiboyina, Shirisha, Fostok, Sabreen, Nasr, Rihab, Lelièvre, Sophie, Talhouk, Rabih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768134/
https://www.ncbi.nlm.nih.gov/pubmed/36539576
http://dx.doi.org/10.1038/s41598-022-25663-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768134/
https://www.ncbi.nlm.nih.gov/pubmed/36539576
http://dx.doi.org/10.1038/s41598-022-25663-8

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