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Fluxomics reveals cellular and molecular basis of increased renal ammoniagenesis

The kidney plays a critical role in excreting ammonia during metabolic acidosis and liver failure. The mechanisms behind this process have been poorly explored. The present study combines results of in vivo experiments of increased total ammoniagenesis with systems biology modeling, in which eight r...

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Detalles Bibliográficos
Autores principales: Mpabanzi, Liliane, Wainwright, Jessica, Boonen, Bas, van Eijk, Hans, Dhar, Dipok, Karssemeijer, Esther, Dejong, Cees H. C., Jalan, Rajiv, Schwartz, Jean-Marc, Olde Damink, Steven W. M., Soons, Zita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768161/
https://www.ncbi.nlm.nih.gov/pubmed/36539425
http://dx.doi.org/10.1038/s41540-022-00257-2