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Fluxomics reveals cellular and molecular basis of increased renal ammoniagenesis
The kidney plays a critical role in excreting ammonia during metabolic acidosis and liver failure. The mechanisms behind this process have been poorly explored. The present study combines results of in vivo experiments of increased total ammoniagenesis with systems biology modeling, in which eight r...
Autores principales: | Mpabanzi, Liliane, Wainwright, Jessica, Boonen, Bas, van Eijk, Hans, Dhar, Dipok, Karssemeijer, Esther, Dejong, Cees H. C., Jalan, Rajiv, Schwartz, Jean-Marc, Olde Damink, Steven W. M., Soons, Zita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768161/ https://www.ncbi.nlm.nih.gov/pubmed/36539425 http://dx.doi.org/10.1038/s41540-022-00257-2 |
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