Fluorinated triphenylphosphonium analogs improve cell selectivity and in vivo detection of mito-metformin

Triphenylphosphonium (TPP(+)) conjugated compounds selectively target cancer cells by exploiting their hyperpolarized mitochondrial membrane potential. To date, studies have focused on modifying either the linker or the cargo of TPP(+)-conjugated compounds. Here, we investigated the biological effec...

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Detalles Bibliográficos
Autores principales: AbuEid, Mahmoud, Keyes, Robert F., McAllister, Donna, Peterson, Francis, Kadamberi, Ishaque Pulikkal, Sprague, Daniel J., Chaluvally-Raghavan, Pradeep, Smith, Brian C., Dwinell, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768319/
https://www.ncbi.nlm.nih.gov/pubmed/36567718
http://dx.doi.org/10.1016/j.isci.2022.105670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768319/
https://www.ncbi.nlm.nih.gov/pubmed/36567718
http://dx.doi.org/10.1016/j.isci.2022.105670

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