Cargando…
Fluorinated triphenylphosphonium analogs improve cell selectivity and in vivo detection of mito-metformin
Triphenylphosphonium (TPP(+)) conjugated compounds selectively target cancer cells by exploiting their hyperpolarized mitochondrial membrane potential. To date, studies have focused on modifying either the linker or the cargo of TPP(+)-conjugated compounds. Here, we investigated the biological effec...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768319/ https://www.ncbi.nlm.nih.gov/pubmed/36567718 http://dx.doi.org/10.1016/j.isci.2022.105670 |