Cargando…

Deletion of classical transient receptor potential 1, 3 and 6 alters pulmonary vasoconstriction in chronic hypoxia-induced pulmonary hypertension in mice

Chronic hypoxia-induced pulmonary hypertension (CHPH) is a severe disease that is characterized by increased proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs) leading to pulmonary vascular remodeling. The resulting increase in pulmonary vascular resistance (PVR) causes r...

Descripción completa

Detalles Bibliográficos
Autores principales: Malkmus, Kathrin, Brosien, Monika, Knoepp, Fenja, Schaffelhofer, Lisa, Grimminger, Friedrich, Rummel, Christoph, Gudermann, Thomas, Dietrich, Alexander, Birnbaumer, Lutz, Weissmann, Norbert, Kraut, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768328/
https://www.ncbi.nlm.nih.gov/pubmed/36569761
http://dx.doi.org/10.3389/fphys.2022.1080875