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Deletion of classical transient receptor potential 1, 3 and 6 alters pulmonary vasoconstriction in chronic hypoxia-induced pulmonary hypertension in mice
Chronic hypoxia-induced pulmonary hypertension (CHPH) is a severe disease that is characterized by increased proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs) leading to pulmonary vascular remodeling. The resulting increase in pulmonary vascular resistance (PVR) causes r...
Autores principales: | Malkmus, Kathrin, Brosien, Monika, Knoepp, Fenja, Schaffelhofer, Lisa, Grimminger, Friedrich, Rummel, Christoph, Gudermann, Thomas, Dietrich, Alexander, Birnbaumer, Lutz, Weissmann, Norbert, Kraut, Simone |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768328/ https://www.ncbi.nlm.nih.gov/pubmed/36569761 http://dx.doi.org/10.3389/fphys.2022.1080875 |
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