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Accurate determination of causalities in gene regulatory networks by dissecting downstream target genes

Accurate determination of causalities between genes is a challenge in the inference of gene regulatory networks (GRNs) from the gene expression profile. Although many methods have been developed for the reconstruction of GRNs, most of them are insufficient in determining causalities or regulatory di...

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Detalles Bibliográficos
Autores principales: Jia, Zhigang, Zhang, Xiujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768335/
https://www.ncbi.nlm.nih.gov/pubmed/36568360
http://dx.doi.org/10.3389/fgene.2022.923339