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The CMV-encoded G protein-coupled receptors M33 and US28 play pleiotropic roles in immune evasion and alter host T cell responses

INTRODUCTION: Human cytomegalovirus (HCMV) is a global health threat due to its ubiquity and lifelong persistence in infected people. During latency, host CD8(+) T cell responses to HCMV continue to increase in a phenomenon known as memory inflation. We used murine CMV (MCMV) as a model for HCMV to...

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Detalles Bibliográficos
Autores principales: White, Timothy M., Bonavita, Cassandra M., Stanfield, Brent A., Farrell, Helen E., Davis-Poynter, Nicholas J., Cardin, Rhonda D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768342/
https://www.ncbi.nlm.nih.gov/pubmed/36569845
http://dx.doi.org/10.3389/fimmu.2022.1047299