Might nontransferrin-bound iron in blood plasma and sera be a nonproteinaceous high-molecular-mass Fe(III) aggregate?

The HFE (Homeostatic Fe regulator) gene is commonly mutated in hereditary hemochromatosis. Blood of (HFE)(−/−) mice and of humans with hemochromatosis contains toxic nontransferrin-bound iron (NTBI) which accumulates in organs. However, the chemical composition of NTBI is uncertain. To investigate,...

Descripción completa

Detalles Bibliográficos
Autores principales: Vali, Shaik Waseem, Lindahl, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768373/
https://www.ncbi.nlm.nih.gov/pubmed/36334631
http://dx.doi.org/10.1016/j.jbc.2022.102667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768373/
https://www.ncbi.nlm.nih.gov/pubmed/36334631
http://dx.doi.org/10.1016/j.jbc.2022.102667

Ejemplares similares