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Brain-derived neurotrophic factor stimulates the retrograde pathway for axonal autophagy

Autophagy is a lysosomal degradation pathway important for neuronal development, function, and survival. How autophagy in axons is regulated by neurotrophins to impact neuronal viability and function is poorly understood. Here, we use live-cell imaging in primary neurons to investigate the regulatio...

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Detalles Bibliográficos
Autores principales: Sidibe, David Kader, Kulkarni, Vineet Vinay, Dong, Audrey, Herr, Jessica Brandt, Vogel, Maria Chalokh, Stempel, Max Henry, Maday, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768381/
https://www.ncbi.nlm.nih.gov/pubmed/36336077
http://dx.doi.org/10.1016/j.jbc.2022.102673