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Generation of orthotopic patient-derived xenograft models for pancreatic cancer using tumor slices
Orthotopic patient-derived xenograft models recapitulate the genomic complexity of the original tumor and some aspects of local microenvironment, useful for rapid development and validation of personalized treatment strategies. Here, we precisely describe a protocol for generating tumor slices from...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768417/ https://www.ncbi.nlm.nih.gov/pubmed/36595938 http://dx.doi.org/10.1016/j.xpro.2022.101899 |