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Generation of orthotopic patient-derived xenograft models for pancreatic cancer using tumor slices

Orthotopic patient-derived xenograft models recapitulate the genomic complexity of the original tumor and some aspects of local microenvironment, useful for rapid development and validation of personalized treatment strategies. Here, we precisely describe a protocol for generating tumor slices from...

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Detalles Bibliográficos
Autores principales:	Curiel-Garcia, Alvaro, Decker-Farrell, Amanda R., Sastra, Stephen A., Olive, Kenneth P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768417/ https://www.ncbi.nlm.nih.gov/pubmed/36595938 http://dx.doi.org/10.1016/j.xpro.2022.101899

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