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Bmpr2 mutant mice are an inadequate model for studying iron deficiency in pulmonary hypertension

As bone morphogenetic protein receptor type II (Bmpr2) mutations are the most common genetic cause of pulmonary arterial hypertension (PAH), and iron deficiency (ID) is associated with worse clinical outcomes in PAH patients, we proposed to use Bmpr2 ± mice to induce a model of ID in pulmonary vascu...

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Detalles Bibliográficos
Autores principales: Zhang, Vida, Ganz, Tomas, Nemeth, Elizabeta, Umar, Soban, Kim, Airie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768458/
https://www.ncbi.nlm.nih.gov/pubmed/36568690
http://dx.doi.org/10.1002/pul2.12151