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Riociguat inhibits ultra‐large VWF string formation on pulmonary artery endothelial cells from chronic thromboembolic pulmonary hypertension patients

Chronic thromboembolic pulmonary hypertension (CTEPH) is characterized by elevated pulmonary arterial pressure and organized thrombi within pulmonary arteries. Riociguat is a soluble guanylate cyclase stimulator and is approved for patients with inoperable CTEPH or residual pulmonary hypertension af...

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Detalles Bibliográficos
Autores principales: Jujo Sanada, Takayuki, Manz, Xue D., Symersky, Petr, Pan, Xiaoke, Yoshida, Keimei, Aman, Jurjan, Bogaard, Harm Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768460/
https://www.ncbi.nlm.nih.gov/pubmed/36568694
http://dx.doi.org/10.1002/pul2.12146