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Translation in the cell under fierce competition for shared resources: a mathematical model
During translation, mRNAs ‘compete’ for shared resources. Under stress conditions, during viral infection and also in high-throughput heterologous gene expression, these resources may become scarce, e.g. the pool of free ribosomes is starved, and then the competition may have a dramatic effect on th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768467/ https://www.ncbi.nlm.nih.gov/pubmed/36541059 http://dx.doi.org/10.1098/rsif.2022.0535 |