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Translation in the cell under fierce competition for shared resources: a mathematical model

During translation, mRNAs ‘compete’ for shared resources. Under stress conditions, during viral infection and also in high-throughput heterologous gene expression, these resources may become scarce, e.g. the pool of free ribosomes is starved, and then the competition may have a dramatic effect on th...

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Detalles Bibliográficos
Autores principales: Katz, Rami, Attias, Elad, Tuller, Tamir, Margaliot, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768467/
https://www.ncbi.nlm.nih.gov/pubmed/36541059
http://dx.doi.org/10.1098/rsif.2022.0535