Patient-specific and gene-corrected induced pluripotent stem cell-derived endothelial cells elucidate single-cell phenotype of pulmonary veno-occlusive disease

Pulmonary veno-occlusive disease (PVOD) is a rare form of pulmonary hypertension characterized by the preferential remodeling of the pulmonary venules. Hereditary PVOD is caused by biallelic variants of the EIF2AK4 gene. Three PVOD patients who carried the compound heterozygous variants of EIF2AK4 a...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Baihui, Li, Tianjiao, Li, Wenke, Yang, Hang, Zeng, Qixian, Pan, Zihang, Wang, Kai, Chen, Qianlong, Xiong, Changming, Zhou, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768576/
https://www.ncbi.nlm.nih.gov/pubmed/36400028
http://dx.doi.org/10.1016/j.stemcr.2022.10.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768576/
https://www.ncbi.nlm.nih.gov/pubmed/36400028
http://dx.doi.org/10.1016/j.stemcr.2022.10.014

Ejemplares similares