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Modeling sex differences in humans using isogenic induced pluripotent stem cells
Biological sex is a fundamental trait influencing development, reproduction, pathogenesis, and medical treatment outcomes. Modeling sex differences is challenging because of the masking effect of genetic variability and the hurdle of differentiating chromosomal versus hormonal effects. In this work...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768579/ https://www.ncbi.nlm.nih.gov/pubmed/36427492 http://dx.doi.org/10.1016/j.stemcr.2022.10.017 |