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Modeling sex differences in humans using isogenic induced pluripotent stem cells

Biological sex is a fundamental trait influencing development, reproduction, pathogenesis, and medical treatment outcomes. Modeling sex differences is challenging because of the masking effect of genetic variability and the hurdle of differentiating chromosomal versus hormonal effects. In this work...

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Detalles Bibliográficos
Autores principales: Waldhorn, Ithai, Turetsky, Tikva, Steiner, Debora, Gil, Yaniv, Benyamini, Hadar, Gropp, Michal, Reubinoff, Benjamin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768579/
https://www.ncbi.nlm.nih.gov/pubmed/36427492
http://dx.doi.org/10.1016/j.stemcr.2022.10.017