Cargando…

Modeling sex differences in humans using isogenic induced pluripotent stem cells

Biological sex is a fundamental trait influencing development, reproduction, pathogenesis, and medical treatment outcomes. Modeling sex differences is challenging because of the masking effect of genetic variability and the hurdle of differentiating chromosomal versus hormonal effects. In this work...

Descripción completa

Detalles Bibliográficos
Autores principales:	Waldhorn, Ithai, Turetsky, Tikva, Steiner, Debora, Gil, Yaniv, Benyamini, Hadar, Gropp, Michal, Reubinoff, Benjamin E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Resource
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768579/ https://www.ncbi.nlm.nih.gov/pubmed/36427492 http://dx.doi.org/10.1016/j.stemcr.2022.10.017

Ejemplares similares

Laminin111-based defined culture promoting self-renewing human pluripotent stem cells with properties of the early post-implantation epiblast
por: Gropp, Michal, et al.
Publicado: (2022)

Human iPSC-derived astrocytes from ALS patients with mutated C9ORF72 show increased oxidative stress and neurotoxicity
por: Birger, Anastasya, et al.
Publicado: (2019)

Nutritional requirements of human induced pluripotent stem cells
por: Lyra-Leite, Davi M., et al.
Publicado: (2023)

Standardization of the Teratoma Assay for Analysis of Pluripotency of Human ES Cells and Biosafety of Their Differentiated Progeny
por: Gropp, Michal, et al.
Publicado: (2012)

Scarless Genome Editing of Human Pluripotent Stem Cells via Transient Puromycin Selection
por: Steyer, Benjamin, et al.
Publicado: (2018)

Detecting Genetic Mosaicism in Cultures of Human Pluripotent Stem Cells
por: Baker, Duncan, et al.
Publicado: (2016)

Gastruloid Development Competence Discriminates Different States of Pluripotency
por: Cermola, Federica, et al.
Publicado: (2021)

Nonadhesive Alginate Hydrogels Support Growth of Pluripotent Stem Cell-Derived Intestinal Organoids
por: Capeling, Meghan M., et al.
Publicado: (2019)

Small-Molecule-Driven Hepatocyte Differentiation of Human Pluripotent Stem Cells
por: Siller, Richard, et al.
Publicado: (2015)

GAPTrap: A Simple Expression System for Pluripotent Stem Cells and Their Derivatives
por: Kao, Tim, et al.
Publicado: (2016)

Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics
por: Kooreman, Nigel G., et al.
Publicado: (2017)

High-Throughput and Cost-Effective Characterization of Induced Pluripotent Stem Cells
por: D'Antonio, Matteo, et al.
Publicado: (2017)

A Stem Cell Reporter for Investigating Pluripotency and Self-Renewal in the Rat
por: Meek, Stephen, et al.
Publicado: (2020)

Scalable generation of sensory neurons from human pluripotent stem cells
por: Deng, Tao, et al.
Publicado: (2023)

Cell-Surface Proteomics Identifies Differences in Signaling and Adhesion Protein Expression between Naive and Primed Human Pluripotent Stem Cells
por: Wojdyla, Katarzyna, et al.
Publicado: (2020)

Generation of pancreatic progenitors from human pluripotent stem cells by small molecules
por: Jiang, Yuqian, et al.
Publicado: (2021)

Robotic high-throughput biomanufacturing and functional differentiation of human pluripotent stem cells
por: Tristan, Carlos A., et al.
Publicado: (2021)

Human pluripotent stem cell-derived macrophages host Mycobacterium abscessus infection
por: Sun, Shicheng, et al.
Publicado: (2022)

Analysis of Induced Pluripotent Stem Cells from a BRCA1 Mutant Family
por: Soyombo, Abigail A., et al.
Publicado: (2013)

Controlling Expansion and Cardiomyogenic Differentiation of Human Pluripotent Stem Cells in Scalable Suspension Culture
por: Kempf, Henning, et al.
Publicado: (2014)

Differentiation of Human Pluripotent Stem Cells into Functional Endothelial Cells in Scalable Suspension Culture
por: Olmer, Ruth, et al.
Publicado: (2018)

Rapid Mast Cell Generation from Gata2 Reporter Pluripotent Stem Cells
por: Kauts, Mari-Liis, et al.
Publicado: (2018)

A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies
por: Karch, Celeste M., et al.
Publicado: (2019)

Agarose microgel culture delineates lumenogenesis in naive and primed human pluripotent stem cells
por: Schindler, Magdalena, et al.
Publicado: (2021)

Efficient conversion of human induced pluripotent stem cells into microglia by defined transcription factors
por: Chen, Shih-Wei, et al.
Publicado: (2021)

The knockdown of H19lncRNA reveals its regulatory role in pluripotency and tumorigenesis of human embryonic carcinoma cells
por: Zeira, Evelyne, et al.
Publicado: (2015)

Analysis of SOX2-Expressing Cell Populations Derived from Human Pluripotent Stem Cells
por: Brafman, David A., et al.
Publicado: (2013)

A Scaled Framework for CRISPR Editing of Human Pluripotent Stem Cells to Study Psychiatric Disease
por: Hazelbaker, Dane Z., et al.
Publicado: (2017)

Pluri-IQ: Quantification of Embryonic Stem Cell Pluripotency through an Image-Based Analysis Software
por: Perestrelo, Tânia, et al.
Publicado: (2017)

Cooperative genetic networks drive embryonic stem cell transition from naïve to formative pluripotency
por: Lackner, Andreas, et al.
Publicado: (2021)

Machine learning-assisted high-content analysis of pluripotent stem cell-derived embryos in vitro
por: Guo, Jianying, et al.
Publicado: (2021)

Defining the nature of human pluripotent stem cell-derived interneurons via single-cell analysis
por: Allison, Thomas, et al.
Publicado: (2021)

A defined roadmap of radial glia and astrocyte differentiation from human pluripotent stem cells
por: Jovanovic, Vukasin M., et al.
Publicado: (2023)

SOX10 Single Transcription Factor-Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells
por: García-León, Juan Antonio, et al.
Publicado: (2018)

Familial Dysautonomia (FD) Human Embryonic Stem Cell Derived PNS Neurons Reveal that Synaptic Vesicular and Neuronal Transport Genes Are Directly or Indirectly Affected by IKBKAP Downregulation
por: Lefler, Sharon, et al.
Publicado: (2015)

Long-Term Expandable SOX9(+) Chondrogenic Ectomesenchymal Cells from Human Pluripotent Stem Cells
por: Umeda, Katsutsugu, et al.
Publicado: (2015)

cGMP-Manufactured Human Induced Pluripotent Stem Cells Are Available for Pre-clinical and Clinical Applications
por: Baghbaderani, Behnam Ahmadian, et al.
Publicado: (2015)

Functional Neurons Generated from T Cell-Derived Induced Pluripotent Stem Cells for Neurological Disease Modeling
por: Matsumoto, Takuya, et al.
Publicado: (2016)

Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium
por: Salomonis, Nathan, et al.
Publicado: (2016)

A Refined Culture System for Human Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Organoids
por: Takahashi, Yu, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_kfohoeiqs9p25co8ckho616j7g