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Laminin111-based defined culture promoting self-renewing human pluripotent stem cells with properties of the early post-implantation epiblast

In the mammalian embryo, a formative pluripotent phase is proposed to exist at the early post-implantation period, during the transition from the pre-implantation naive—to the post-implantation primed—epiblast. By recapitulating a laminin component of the extracellular matrix niche during embryonic...

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Detalles Bibliográficos
Autores principales: Gropp, Michal, Waldhorn, Ithai, Gil, Yaniv, Steiner, Debora, Turetsky, Tikva Tako, Smith, Yoav, Sabag, Ofra, Falick-Michaeli, Tal, Ram, Sharona Even, Reubinoff, Benjamin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768580/
https://www.ncbi.nlm.nih.gov/pubmed/36368331
http://dx.doi.org/10.1016/j.stemcr.2022.10.010