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Laminin111-based defined culture promoting self-renewing human pluripotent stem cells with properties of the early post-implantation epiblast
In the mammalian embryo, a formative pluripotent phase is proposed to exist at the early post-implantation period, during the transition from the pre-implantation naive—to the post-implantation primed—epiblast. By recapitulating a laminin component of the extracellular matrix niche during embryonic...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768580/ https://www.ncbi.nlm.nih.gov/pubmed/36368331 http://dx.doi.org/10.1016/j.stemcr.2022.10.010 |