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Maternal Western-style diet remodels the transcriptional landscape of fetal hematopoietic stem and progenitor cells in rhesus macaques

Maternal obesity adversely impacts the in utero metabolic environment, but its effect on fetal hematopoiesis remains incompletely understood. During late development, the fetal bone marrow (FBM) becomes the major site where macrophages and B lymphocytes are produced via differentiation of hematopoie...

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Detalles Bibliográficos
Autores principales: Sureshchandra, Suhas, Chan, Chi N., Robino, Jacob J., Parmelee, Lindsay K., Nash, Michael J., Wesolowski, Stephanie R., Pietras, Eric M., Friedman, Jacob E., Takahashi, Diana, Shen, Weining, Jiang, Xiwen, Hennebold, Jon D., Goldman, Devorah, Packwood, William, Lindner, Jonathan R., Roberts, Charles T., Burwitz, Benjamin J., Messaoudi, Ilhem, Varlamov, Oleg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768582/
https://www.ncbi.nlm.nih.gov/pubmed/36332628
http://dx.doi.org/10.1016/j.stemcr.2022.10.003