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TLR ligand ligation switches adenosine receptor usage of BMDCs leading to augmented Th17 responses in experimental autoimmune uveitis

The extracellular level of adenosine increases greatly during inflammation, which modulates immune responses. We have previously reported that adenosine enhances Th17 responses while it suppresses Th1 responses. This study examined whether response of DC to adenosine contributes to the biased effect...

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Detalles Bibliográficos
Autores principales: Sun, Deming, Shao, Hui, Kaplan, Henry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768583/
https://www.ncbi.nlm.nih.gov/pubmed/36569633
http://dx.doi.org/10.1016/j.crimmu.2022.04.001