Sonic hedgehog is basolaterally sorted from the TGN and transcytosed to the apical domain involving Dispatched-1 at Rab11-ARE

Hedgehog proteins (Hhs) secretion from apical and/or basolateral domains occurs in different epithelial cells impacting development and tissue homeostasis. Palmitoylation and cholesteroylation attach Hhs to membranes, and Dispatched-1 (Disp-1) promotes their release. How these lipidated proteins are...

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Detalles Bibliográficos
Autores principales: Sandoval, Lisette, Labarca, Mariana, Retamal, Claudio, Sánchez, Paula, Larraín, Juan, González, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768590/
https://www.ncbi.nlm.nih.gov/pubmed/36568977
http://dx.doi.org/10.3389/fcell.2022.833175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768590/
https://www.ncbi.nlm.nih.gov/pubmed/36568977
http://dx.doi.org/10.3389/fcell.2022.833175

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