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Characterization of insulin crystalline form in isolated β-cell secretory granules

Insulin is stored in vivo inside the pancreatic β-cell insulin secretory granules. In vitro studies have led to an assumption that high insulin and Zn(2+) concentrations inside the pancreatic β-cell insulin secretory granules should promote insulin crystalline state in the form of Zn(2+)-stabilized...

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Detalles Bibliográficos
Autores principales: Asai, Seiya, Moravcová, Jana, Žáková, Lenka, Selicharová, Irena, Hadravová, Romana, Brzozowski, Andrzej Marek, Nováček, Jiří, Jiráček, Jiří
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768635/
https://www.ncbi.nlm.nih.gov/pubmed/36541100
http://dx.doi.org/10.1098/rsob.220322