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Characterization of insulin crystalline form in isolated β-cell secretory granules
Insulin is stored in vivo inside the pancreatic β-cell insulin secretory granules. In vitro studies have led to an assumption that high insulin and Zn(2+) concentrations inside the pancreatic β-cell insulin secretory granules should promote insulin crystalline state in the form of Zn(2+)-stabilized...
Autores principales: | Asai, Seiya, Moravcová, Jana, Žáková, Lenka, Selicharová, Irena, Hadravová, Romana, Brzozowski, Andrzej Marek, Nováček, Jiří, Jiráček, Jiří |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768635/ https://www.ncbi.nlm.nih.gov/pubmed/36541100 http://dx.doi.org/10.1098/rsob.220322 |
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