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An End Point-Specific Framework for Read-Across Analog Selection for Human Health Effects

[Image: see text] Integrating computational chemistry and toxicology can improve the read-across analog approach to fill data gaps in chemical safety assessment. In read-across, structure-related parameters are compared between a target chemical with insufficient test data and one or more materials...

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Detalles Bibliográficos
Autores principales: Moustakas, Holger, Date, Mihir S., Kumar, Manoj, Schultz, Terry W., Liebler, Daniel C., Penning, Trevor M., Salvito, Daniel T., Api, Anne Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768807/
https://www.ncbi.nlm.nih.gov/pubmed/36458907
http://dx.doi.org/10.1021/acs.chemrestox.2c00286