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An Efficient and Sustainable Synthesis of the Antimalarial Drug Tafenoquine
[Image: see text] An 11-step, 8-pot synthesis of the antimalarial drug tafenoquine succinate was achieved in 42% overall yield using commercially available starting materials. Compared to the previous manufacturing processes that utilize environmentally egregious organic solvents and toxic reagents,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768812/ https://www.ncbi.nlm.nih.gov/pubmed/36569493 http://dx.doi.org/10.1021/acssuschemeng.2c05628 |