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Pathways to Identify Electrophiles In Vivo Using Hemoglobin Adducts: Hydroxypropanoic Acid Valine Adduct and Its Possible Precursors

[Image: see text] Analytical methods and tools for the characterization of the human exposome by untargeted mass spectrometry approaches are advancing rapidly. Adductomics methods have been developed for untargeted screening of short-lived electrophiles, in the form of adducts to proteins or DNA, in...

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Detalles Bibliográficos
Autores principales: Vryonidis, Efstathios, Karlsson, Isabella, Aasa, Jenny, Carlsson, Henrik, Motwani, Hitesh V., Pedersen, Marie, Eriksson, Johan, Törnqvist, Margareta Å.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768813/
https://www.ncbi.nlm.nih.gov/pubmed/36395356
http://dx.doi.org/10.1021/acs.chemrestox.2c00208