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Identification of new inhibitors of NS5 from dengue virus using saturation transfer difference (STD-NMR) and molecular docking studies

The rapid spread of dengue virus has now emerged as a major health problem worldwide, particularly in tropical and sub-tropical regions. Nearly half of the human population is at risk of getting infection. Among the proteomes of dengue virus, nonstructural protein NS5 is conserved across the genus F...

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Detalles Bibliográficos
Autores principales: Ullah, Asmat, Atia-tul-Wahab, Gong, Peng, Khan, Abdul Mateen, Choudhary, M. Iqbal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768849/
https://www.ncbi.nlm.nih.gov/pubmed/36605638
http://dx.doi.org/10.1039/d2ra04836a