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Cyclophilin A causes severe fever with thrombocytopenia syndrome virus-induced cytokine storm by regulating mitogen-activated protein kinase pathway

INTRODUCTION: Severe fever with thrombocytopenia syndrome (SFTS) has become a global threat to public health since its first report in China in 2009. However, the pathogenesis of SFTS virus (SFTSV) in humans remains unclear. Also, there are no effective therapeutics for SFTS. Cyclophilin A (CyPA) re...

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Detalles Bibliográficos
Autores principales: Huang, Huaying, Jin, Ke, Ouyang, Ke, Jiang, Zhengyi, Yang, Zhan, Hu, Nannan, Dai, Yan, Zhang, Yaqin, Zhang, Qian, Han, Ying, Zhao, Jie, Lin, Hong, Wang, Chunhui, Wang, Chunyan, Sun, Xuewei, Lu, Dafeng, Zhu, Jin, Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768865/
https://www.ncbi.nlm.nih.gov/pubmed/36569095
http://dx.doi.org/10.3389/fmicb.2022.1046176