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Constitutive glucose dehydrogenase elevates intracellular NADPH levels and luciferase luminescence in Bacillus subtilis

BACKGROUND: Genetic modifications in Bacillus subtilis have allowed the conversion of myo-inositol into scyllo-inositol, which is proposed as a therapeutic agent for Alzheimer’s disease. This conversion comprises two reactions catalyzed by two distinct inositol dehydrogenases, IolG and IolW. The Iol...

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Detalles Bibliográficos
Autores principales: Wu, Yuzheng, Kawabata, Honami, Kita, Kyosuke, Ishikawa, Shu, Tanaka, Kan, Yoshida, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768902/
https://www.ncbi.nlm.nih.gov/pubmed/36539761
http://dx.doi.org/10.1186/s12934-022-01993-0